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KMID : 0370920090260020093
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Yeungnam Univercity Journal of Medicine
2009 Volume.26 No. 2 p.93 ~ p.101
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Use of Magnesium in Anesthesiology and Pain Medicine
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Seong Chae-Rim
Jee Dae-Lim
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Abstract
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The use of magnesium sulphate has recently increased in anesthesiology and pain medicine. The roles of magnesium sulphate are as an analgesic adjuvant, a vasodilator, a calcium channel blocker and reducing the anesthetic requirement. These effect are primarily based on the regulation of calcium influx into the cell and antagonism of the N-methyl-D-aspartate receptor. We discuss here the clinical effects of magnesium sulphate on anesthesiology and pain medicine.
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KEYWORD
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Magnesium sulphate, Calcium channel blocker, N-methyl-D-aspartate
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